Does hCG increase anxiety?

The prescribing information for hCG lists irritability, restlessness, depression and fatigue among reported adverse reactions, along with headache, fluid retention and, in men, breast tissue growth. Some of these may track hormone changes, since hCG raises testosterone, which can convert to estrogen. Anxiety itself isn’t a well-studied endpoint, and no controlled data measure it. Reported reactions vary by indication.

Those reports describe the prescription drug under medical supervision, not research material. In research models, hCG is a tool for studying the LH/hCG receptor, Leydig cell testosterone output and ovarian signaling. The HCG 5000 IU we sell isn’t for human use, and we give no protocols. Every lot is tested, with reports in our COA library. Shop HCG for laboratory research.