What does peptide ipamorelin do?

Ipamorelin is a synthetic five-residue peptide that binds the ghrelin receptor (GHS-R1a) on pituitary cells and triggers growth hormone release. Novo Nordisk developed it in the 1990s, and Raun et al. (1998) called it the first selective growth hormone secretagogue. In pigs, it raised growth hormone without raising ACTH, cortisol or prolactin, unlike GHRP-6 and GHRP-2.

In healthy volunteers, each dose produced a single growth hormone pulse that returned to baseline within hours, with a half-life of about two hours. In rats, it increased bone growth in length. Its main clinical program, for gut slowdown after surgery, missed its primary endpoint. It’s sold here as 10 mg of lyophilized powder for laboratory research. Read our research purposes only policy, then shop Ipamorelin Peptide.